Article
The caregene study: muscle-specific creatine kinase gene and aerobic power in coronary artery disease.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology - 1 Aug 2005
Defoor Johan, Martens Kevin, Matthijs Gert, Zieliñska Dominika, Schepers Dirk, Philips Tim, Vlietinck Robert, Fagard Robert, Vanhees Luc
Abstract excerpt
In 927 biologically unrelated Caucasian patients with coronary artery disease it was investigated whether the NcoI restriction fragment length polymorphism of the muscle-specific creatine kinase (CKMM) gene is associated with aerobic power and with the response to physical training. Physical training significantly (P<0.001) increased peak oxygen consumption in the GG, AG and AA NcoI genotypes. Covariate-adjusted...
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