Article
The evaluation of gastric cancer sensitivity to 5-FU/CDDP in terms of induction of apoptosis: time- and p53 expression-dependency of anti-cancer drugs.
Oncology reports - 1 Sept 2005
Matsuhashi Nobuhisa, Saio Masanao, Matsuo Atsushi, Sugiyama Yasuyuki, Saji Shigetoyo
Abstract excerpt
Clinical in vivo and in vitro studies have revealed pronounced gastric cancer activity using the combination of 5-fluorouracil (5-FU) and cisplatin (CDDP). In addition, the combination of 5-fluorouracil plus cisplatin (FP treatment) possesses synergistic cytotoxicity against gastric cancer. Sensi...
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