Article
Norrie disease gene sequence variants in an ethnically diverse population with retinopathy of prematurity.
Molecular vision - 14 Jul 2005
Hutcheson Kelly A, Paluru Prasuna C, Bernstein Steven L, Koh Jamie, Rappaport Eric F, Leach Richard A, Young Terri L
Abstract excerpt
PURPOSE: Retinopathy of prematurity (ROP) is a leading cause of visual loss in the pediatric population. Mutations in the Norrie disease gene (NDP) are associated with heritable retinal vascular disorders, and have been found in a small subset of patients with severe retinopathy of prematurity. Varying rates of progression to threshold disease in different races may have a genetic basis, as recent studies suggest...
Topics
- 3' Untranslated Regions
- 5' Untranslated Regions
- Adult
- Black or African American
- Case-Control Studies
- Cohort Studies
- DNA Transposable Elements
- Exons
- Eye Proteins
- Female
- Gene Deletion
- Heterozygote
- Humans