Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple lipomas, alcoholism, and neuropathy: Madelung's disease or MERRF?

Muscle & nerve - 1 Jan 2006

Schoffer Kerrie, Grant Ian

Abstract excerpt

We report a 51-year-old alcoholic man with a 10-year history of cervical lipomas and progressive symmetrical sensory neuropathy, initially diagnosed with Madelung's disease, an idiopathic syndrome often attributed to chronic alcoholism. The eventual development of proximal weakness led to pathological and genetic testing which identified a A8344G mutation in the mitochondrial tRNA lysine gene, associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Lipoma
Share to MERRF Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Skeletal

Share to Mutation

Share to RNA, Mitochondrial

Share to RNA, Transfer, Lys

Source

Identifiers

PMID: 16007676
DOI: 10.1002/mus.20406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple lipomas, alcoholism, and neuropathy: Madelung's disease or MERRF?PMID 16007676Read ↗

Beyond cervical lipomas: myoclonus, gait disorder and multisystem involvement leading to mitochondrial disease.Semantic proximity Read ↗

Multiple Symmetric Lipomatosis (Madelung's Disease) Caused by the MERRF (A8344G) MutationSemantic proximity Read ↗

Madelung's disease associated with polyneuropathy and symptomatic hypokalemia.Semantic proximity Read ↗

Multiple symmetric lipomatosis type I in a female patient with neuropathy: no association with alcoholism or mitochondrial DNA m.8344A>G mutation.Semantic proximity Read ↗

Multiple symmetric lipomas with high levels of mtDNA with the tRNA(Lys) A-->G(8344) mutation as the only manifestation of disease in a carrier of myoclonus epilepsy and ragged-red fibers (MERRF) syndrome.Semantic proximity Read ↗

Multiple Symmetric Lipomatosis (Madelung Disease) in a Large Canadian Family With the Mitochondrial MTTK c.8344A>G VariantSemantic proximity Read ↗

Benign symmetric lipomatosis with axonal neuropathy and abnormalities in specific mitochondrial tRNA regions.Semantic proximity Read ↗

Lipomatosis Incidence and Characteristics in an Italian Cohort of Mitochondrial PatientsSemantic proximity Read ↗

Lipomatosis and optic neuropathy clinches the diagnosis of myoclonic epilepsy with ragged red fibres (MERRF) syndrome.Semantic proximity Read ↗

Familial multiple symmetric lipomatosis associated with the A8344G mutation of mitochondrial DNASemantic proximity Read ↗

Mitochondrial DNA mutations in multiple symmetric lipomatosis.Semantic proximity Read ↗

Cerebellar ataxia, myoclonus, cervical lipomas, and MERRF syndrome. Case report.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.