Article
Multiple and highly divergent IL-11 genes in teleost fish.
Immunogenetics - 1 Jul 2005
Huising Mark O, Kruiswijk Corine P, van Schijndel Jessica E, Savelkoul Huub F J, Flik Gert, Verburg-van Kemenade B M Lidy
Abstract excerpt
Interleukin-11 (IL-11) is a key cytokine in the regulation of proliferation and differentiation of hematopoietic progenitors and is also involved in bone formation, adipogenesis, and protection of mucosal epithelia. Despite this prominent role in diverse physiological processes, IL-11 has been described in only four mammalian species, and recently, in rainbow trout (Oncorhynchus mykiss). Here we report the...
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