Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a mutation in the gene encoding the alpha subunit of the stimulatory G protein of adenylyl cyclase in McCune-Albright syndrome.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1992

Schwindinger W F, Francomano C A, Levine M A

Abstract excerpt

McCune-Albright syndrome (MAS) is characterized by polyostotic fibrous dysplasia, café-au-lait lesions, and a variety of endocrine disorders, including precocious puberty, hyperthyroidism, hypercortisolism, growth hormone excess, and hyperprolactinemia. The diverse metabolic abnormalities seen in MAS share the involvement of cells that respond to extracellular signals through activation of the hormone-sensitive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to Molecular Sequence Data

Share to Mutation

Share to Oligodeoxyribonucleotides

Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 1594625
DOI: 10.1073/pnas.89.11.5152
PMCID: PMC49247

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a mutation in the gene encoding the alpha subunit of the stimulatory G protein of adenylyl cyclase in McCune-Albright syndrome.PMID 1594625Read ↗

Activating mutations of the stimulatory G protein in the McCune-Albright syndrome.Semantic proximity Read ↗

Activating Gsalpha mutations: analysis of 113 patients with signs of McCune-Albright syndrome--a European Collaborative Study.Semantic proximity Read ↗

An activating Gs alpha mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome.Semantic proximity Read ↗

A Novel GNAS1 Mutation, R201G, in McCune–Albright SyndromeSemantic proximity Read ↗

G(s)alpha mutations in fibrous dysplasia and McCune-Albright syndrome.Semantic proximity Read ↗

McCune-Albright Syndrome: A Detailed Pathological and Genetic Analysis of Disease Effects in an Adult PatientSemantic proximity Read ↗

Multidisciplinary approach and clinical management of McCune-Albright syndrome.Semantic proximity Read ↗

Clinical implications of genetic defects in G proteins. The molecular basis of McCune-Albright syndrome and Albright hereditary osteodystrophy.Semantic proximity Read ↗

Mutations of the GNAS1 gene, stromal cell dysfunction, and osteomalacic changes in non-McCune-Albright fibrous dysplasia of bone.Semantic proximity Read ↗

Fibrous Dysplasia/McCune-Albright Syndrome: A Rare, Mosaic Disease of Gα s ActivationSemantic proximity Read ↗

Fibrous dysplasia/McCune-Albright syndrome: state-of-the-art advances, pathogenesis, and basic/translational researchSemantic proximity Read ↗

Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.