Article
Inferring the connectivity of a regulatory network from mRNA quantification in Synechocystis PCC6803.
Nucleic acids research - 1 Jan 2005
Lemeille Sylvain, Latifi Amel, Geiselmann Johannes
Abstract excerpt
A major task of contemporary biology is to understand and predict the functioning of regulatory networks. We use expression data to deduce the regulation network connecting the sigma factors of Synechocystis PCC6803, the most global regulators in bacteria. Synechocystis contains one group 1 (SigA) and four group 2 (SigB, SigC, SigD and SigE) sigma factors. From the relative abundance of the sig mRNA measured in...
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