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Increased Cardiomyocyte Differentiation from Human Embryonic Stem Cells in Serum‐Free Cultures

25 May 2005

Abstract excerpt

Human embryonic stem cells (hESCs) can differentiate into cardiomyocytes, but the efficiency of this process is low. We routinely induce cardiomyocyte differentiation of the HES-2 cell line by coculture with a visceral endoderm-like cell line, END-2, in the presence of 20% fetal calf serum (FCS). In this study, we demonstrate a striking inverse relationship between cardiomyocyte differentiation and the...

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PMID: 15917473
DOI: 10.1634/stemcells.2004-0184

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