Article
Two acid-inducible promoters from Lactococcus lactis require the cis-acting ACiD-box and the transcription regulator RcfB.
Molecular microbiology - 1 May 2005
Madsen Søren M, Hindré Thomas, Le Pennec Jean-Paul, Israelsen Hans, Dufour Alain
Abstract excerpt
We previously characterized three Lactococcus lactis promoters, P170, P1 and P3, which are induced by low pH. Here, we identified a novel 14 bp regulatory DNA region centred at around -41.5 and composed of three tetranucleotide sequences, boxes A, C and D. Boxes A and C contribute to P1 activity, whereas box D and the position of boxes ACD (renamed ACiD-box) are essential to P1 activity and acid response. We also...
Topics
- Acids
- Bacterial Proteins
- Bacteriocins
- Base Sequence
- Carrier Proteins
- Chaperonin 60
- DNA Transposable Elements
- Gene Expression Regulation, Bacterial
- Gene Silencing
- Genes, Regulator
- Lactococcus lactis
- Molecular Sequence Data
- Mutation
- Operon