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Article

Possible evidence for genomic imprinting in childhood acute myeloblastic leukaemia associated with monosomy for chromosome 7.

British journal of haematology - 1 Mar 1992

Katz F, Webb D, Gibbons B, Reeves B, McMahon C, Chessells J, Mitchell C

Abstract excerpt

Monosomy or deletion of chromosome 7 is a frequent finding in both de novo and secondary acute myeloid leukaemia (AML) and myelodysplastic syndromes (MDS). Based on analysis of deletions of chromosome 7 in such patients, it has been suggested that there is a critical region of the chromosome lying within bands q21-q31. We have examined bone marrow and peripheral blood samples from 10 patients with MDS, AML and...

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Identifiers

PMID: 1581212
DOI: 10.1111/j.1365-2141.1992.tb08141.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Possible evidence for genomic imprinting in childhood acute myeloblastic leukaemia associated with monosomy for chromosome 7.PMID 1581212Read ↗

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The enigma of monosomy 7Semantic proximity Read ↗

Loss of maternal allele in a child with myelodysplastic syndrome and monosomy 7.Semantic proximity Read ↗

Prevalence of germline GATA2 and SAMD9/9L variants in paediatric haematological disorders with monosomy 7Semantic proximity Read ↗

Allelotyping of acute myelogenous leukemia: loss of heterozygosity at 7q31.1 (D7S486) and q33-34 (D7S498, D7S505).Semantic proximity Read ↗

Mutations of the ras proto-oncogenes in childhood monosomy 7.Semantic proximity Read ↗

Familial partial monosomy 7 and myelodysplasia: different parental origin of the monosomy 7 suggests action of a mutator gene.Semantic proximity Read ↗

Myelodysplastic syndrome, juvenile myelomonocytic leukemia, and acute myeloid leukemia associated with complete or partial monosomy 7. European Working Group on MDS in Childhood (EWOG-MDS).Semantic proximity Read ↗

Monosomy 7 and deletion 7q in children and adolescents with acute myeloid leukemia: an international retrospective studySemantic proximity Read ↗

Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis.Semantic proximity Read ↗

Granulocyte colony-stimulating factor preferentially stimulates proliferation of monosomy 7 cells bearing the isoform IV receptorSemantic proximity Read ↗

Monosomy 7 and 7q- associated with myeloid malignancySemantic proximity Read ↗

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