Article
Possible evidence for genomic imprinting in childhood acute myeloblastic leukaemia associated with monosomy for chromosome 7.
British journal of haematology - 1 Mar 1992
Katz F, Webb D, Gibbons B, Reeves B, McMahon C, Chessells J, Mitchell C
Abstract excerpt
Monosomy or deletion of chromosome 7 is a frequent finding in both de novo and secondary acute myeloid leukaemia (AML) and myelodysplastic syndromes (MDS). Based on analysis of deletions of chromosome 7 in such patients, it has been suggested that there is a critical region of the chromosome lyin...
Topics
- Acute Disease
- Alleles
- Bone Marrow
- Child
- Child, Preschool
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 7
- DNA
- Female
- Genome, Human
- Humans
- Infant
- Karyotyping
- Leukemia
- Leukemia, Myeloid, Acute
- Male
- Monosomy