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Article

WASP-related proteins, Abi1 and Ena/VASP are required forListeriainvasion induced by the Met receptor

16 Mar 2005

Abstract excerpt

Internalisation of the pathogenic bacterium Listeria monocytogenes involves interactions between the invasion protein InlB and the hepatocyte growth factor receptor, Met. Using colocalisation studies, dominant-negative constructs and small interfering RNA (siRNA), we demonstrate a cell-type-dependent requirement for various WASP-related proteins in Listeria entry and InlB-induced membrane ruffling. The WAVE2...

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PMID: 15769844
DOI: 10.1242/jcs.02285

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