Article
New insights into iron homeostasis through the study of non-HFE hereditary haemochromatosis.
Best practice & research. Clinical haematology - 1 Jun 2005
Roetto Antonella, Camaschella Clara
Abstract excerpt
Non-HFE haemochromatosis is a negative definition applied to all those haemochromatosis disorders that are unrelated to HFE mutations. Four genes are responsible for the distinct types of non-HFE haemochromatosis: hepcidin and hemojuvelin are the genes involved in type 2 or juvenile haemochromatosis, transferrin receptor 2 is involved in type 3 haemochromatosis, and ferroportin 1 is mutated in type 4, the...
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