Article
Prophylactic mastectomy: indications, options, and reconstructive alternatives.
Plastic and reconstructive surgery - 1 Mar 2005
Spear Scott L, Carter Mary Ella, Schwarz Karl
Abstract excerpt
Prophylactic mastectomy continues to be a controversial procedure as a preventive tool against breast cancer. Recent research and other scientific advances, however, have refocused attention on better risk estimation, evidence of efficacy, and improvements in reconstruction. The recently discovered genetic markers BRCA1 and BRCA2 have become increasingly important in determining risk; a BRCA1-positive patient's...
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