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Article

Soft sweeps: molecular population genetics of adaptation from standing genetic variation.

Genetics - 1 Apr 2005

Hermisson Joachim, Pennings Pleuni S

Abstract excerpt

A population can adapt to a rapid environmental change or habitat expansion in two ways. It may adapt either through new beneficial mutations that subsequently sweep through the population or by using alleles from the standing genetic variation. We use diffusion theory to calculate the probabilities for selective adaptations and find a large increase in the fixation probability for weak substitutions, if alleles...

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Identifiers

PMID: 15716498
DOI: 10.1534/genetics.104.036947
PMCID: PMC1449620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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