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Article

Association between Beckwith-Wiedemann syndrome and assisted reproductive technology: a case series of 19 patients.

Fertility and sterility - 1 Feb 2005

Chang Aimee S, Moley Kelle H, Wangler Michael, Feinberg Andrew P, Debaun Michael R

Abstract excerpt

OBJECTIVE: An association between assisted reproductive technique (ART) and specific imprinting mutations, such as Beckwith-Wiedemann syndrome (BWS), has recently been documented. Based on experiments in farm animals that demonstrated an association between alterations in culture media during ART and large offspring syndrome, we hypothesized that the culture media could be implicated as a common factor among the...

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Identifiers

PMID: 15705373
DOI: 10.1016/j.fertnstert.2004.07.964
PMCID: PMC4872595

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clinical and molecular analyses of Beckwith-Wiedemann syndrome: Comparison between spontaneous conception and assisted reproduction techniques.Semantic proximity Read ↗

Large offspring syndromeSemantic proximity Read ↗

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Clinical and molecular genetic features of Beckwith-Wiedemann syndrome associated with assisted reproductive technologies.Semantic proximity Read ↗

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