Article
Mutation rate at commonly used forensic STR loci: paternity testing experience.
Disease markers - 1 Jan 2004
Aşicioglu Faruk, Oguz-Savran Fatma, Ozbek Ugur
Abstract excerpt
Paternity tests are carried out by the analysis of hypervariable short tandem repeat DNA loci. These microsatellite sequences mutate at a higher rate than that of bulk DNA. The occurrence of germline mutations at STR loci posses problems in interpretation of resulting genetic profiles. We recently analyzed 59-159 parent/child allele transfers at 13 microsatellite loci. We identified 12 mutations in 7...
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