Article
Hypothalamic hamartomas and seizures: distinct natural history of isolated and Pallister-Hall syndrome cases.
Epilepsia - 1 Jan 2005
Boudreau Eilis A, Liow Kore, Frattali Carol M, Wiggs Edith, Turner Joyce T, Feuillan Penelope, Sato Susumu, Patsalides Athos, Patronas Nicholas, Biesecker Leslie G, Theodore William H
Abstract excerpt
PURPOSE: Hypothalamic hamartomas (HHs) have been associated with uncontrolled seizures, and aggressive therapy including surgery is often recommended. However, some patients, particularly those with other findings associated with Pallister-Hall syndrome (PHS), have a more benign course. METHODS: Thirty-seven of 40 PHS patients and 16 of 16 patients with isolated HH had a lesion confirmed on magnetic resonance...
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