Reduced bone density in cystic fibrosis: DeltaF508 mutation is an independent risk factor.

doi:10.1183/09031936.04.00050204

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Article

Reduced bone density in cystic fibrosis: DeltaF508 mutation is an independent risk factor.

The European respiratory journal - 1 Jan 2005

King S J, Topliss D J, Kotsimbos T, Nyulasi I B, Bailey M, Ebeling P R, Wilson J W

Abstract excerpt

The aim of this cross-sectional study was to determine the prevalence and identify determinants of reduced bone mineral density (BMD) in adults with cystic fibrosis (CF). Adults (88) with CF (mean+/-SD age 29.9+/-7.7 yrs; forced expiratory volume in one second (FEV1) 58.2+/-21.5% of the predicted value) were studied. BMD at the lumbar spine (LS) and femoral neck (FN) and body composition were measured using...

Topics

Adult
Bone Density
Comorbidity
Cross-Sectional Studies
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Densitometry
Female
Genetic Predisposition to Disease
Humans
Linear Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Multivariate Analysis

Mutation

Osteoporosis

Prevalence

Probability

Prognosis

Source

Open in PubMed

Identifiers

PMID: 15640323
DOI: 10.1183/09031936.04.00050204

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