Recent developments in gene transfer: risk and ethics

Abstract excerpt

Since the early 1990s, investigators have toiled to establish the transfer of genes to human somatic cells as a valid therapy (fig 1). The potential of gene transfer was highlighted by three trials, involving participants with haemophilia B and two types of severe combined immunodeficiency—X linked and adenosine deaminase deficient.1–3 Yet even the most successful trials of gene transfer have engendered questions...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biomedical Ethics and Regulation
• Share to CRISPR and Genetic Engineering
• Share to Virus-based gene therapy research