Article
Lymphocyte function-associated antigen-1 expression on plasma cells correlates with tumor growth in multiple myeloma.
Blood - 15 Apr 1992
Ahsmann E J, Lokhorst H M, Dekker A W, Bloem A C
Abstract excerpt
Lymphocyte function-associated antigen-1 (LFA-1) (CD11a/CD18) expression on bone marrow-derived plasma cells from normal individuals, patients with monoclonal gammopathies of undetermined significance (MGUS), and patients with multiple myeloma (MM) was studied by immunofluorescence microscopy and flow cytometry using a new monoclonal antibody (MoAb) F8.8. This MoAb recognizes the alpha-chain (CD11a) of LFA-1 as...
Topics
- Antibodies, Monoclonal
- Antigens, CD
- Biomarkers, Tumor
- Bone Marrow
- Cytotoxicity, Immunologic
- Female
- Fluorescent Antibody Technique
- Follow-Up Studies
- Hematopoietic Stem Cells
- Humans
- Immunoglobulins
