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Article

Factor V Leiden mutation in relation to fecundity and miscarriage in women with venous thrombosis.

Human reproduction (Oxford, England) - 1 Mar 2005

van Dunné F M, Doggen C J M, Heemskerk M, Rosendaal F R, Helmerhorst F M

Abstract excerpt

BACKGROUND: Factor V Leiden mutation (Arg506Gln) increases the likelihood of venous thrombosis; it may also have a positive effect through facilitation of embryo implantation. This may manifest itself as a reduced time to pregnancy (increased fecundity) and fewer miscarriages in the first trimest...

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Source

Identifiers

PMID: 15618258
DOI: 10.1093/humrep/deh640

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15618258-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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