Article
Cytomegalovirus (CMV) glycoprotein B genotype and CMV DNA load in the amniotic fluid of infected fetuses.
Prenatal diagnosis - 15 Dec 2004
Picone Olivier, Costa Jean-Marc, Leruez-Ville Marianne, Ernault Pauline, Olivi Martine, Ville Yves
Abstract excerpt
OBJECTIVE: To assess the value of both cytomegalovirus (CMV) DNA quantification in amniotic fluid (AF) and CMV glycoprotein B (gB) genotype as prognostic factors in CMV congenital infection. METHODS: Quantification of CMV DNA was performed prospectively by real-time PCR and gB genotypes were analysed by gene sequencing analysis in the amniotic fluid of 42 fetuses infected by CMV. These were correlated with...
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