Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Patterns of cell death triggered in two different cell lines by HypF‐N prefibrillar aggregates

16 Dec 2004

Abstract excerpt

The finding that aggregates of disease-unrelated proteins can induce cell death indicates that proteins may act as potential toxins. Cells experiencing toxic protein aggregates often display modifications of the redox status and ion balance, eventually leading to apoptosis; however, in some cases, tissue and cultured cell types die with features of necrosis. To elucidate the pathways leading to such different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Glycation End Products research
Share to Alzheimer's disease research and treatments
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15604358
DOI: 10.1096/fj.04-3086fje

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Patterns of cell death triggered in two different cell lines by HypF‐N prefibrillar aggregatesPMID 15604358Read ↗

Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregatesSemantic proximity Read ↗

Aponecrosis: Morphological and biochemical exploration of a syncretic process of cell death sharing apoptosis and necrosisSemantic proximity Read ↗

Intracellular clusterin causes juxtanuclear aggregate formation and mitochondrial alterationSemantic proximity Read ↗

Age-Dependent Increases in Apoptosis/Necrosis Ratios in Human Lymphocytes Exposed to Oxidative StressSemantic proximity Read ↗

Cell toxicity and conformational disease.Semantic proximity Read ↗

Toxicity of protein oligomers is rationalized by a function combining size and surface hydrophobicity.Semantic proximity Read ↗

Regulation of necrosis of H9c2 myogenic cells upon transient energy deprivation. Rapid deenergization of mitochondria precedes necrosis and is controlled by reactive oxygen species, stress kinase JNK, HSP72 and ARC.Semantic proximity Read ↗

Apoptosis-inducing Factor (AIF) and Its Family Member Protein, AMID, Are Rotenone-sensitive NADH:Ubiquinone Oxidoreductases (NDH-2).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.