Article
Carnitine deficiency disorders in children.
Annals of the New York Academy of Sciences - 1 Nov 2004
Stanley Charles A
Abstract excerpt
Mitochondrial oxidation of long-chain fatty acids provides an important source of energy for the heart as well as for skeletal muscle during prolonged aerobic work and for hepatic ketogenesis during long-term fasting. The carnitine shuttle is responsible for transferring long-chain fatty acids across the barrier of the inner mitochondrial membrane to gain access to the enzymes of beta-oxidation. The shuttle...
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