Article
DNA polymorphism of Pvu II site in the lipoprotein lipase gene in patients with non-insulin dependent diabetes mellitus.
Cell biochemistry and function - 1 Jan 2000
Süsleyici Duman Belgin, Oztürk Melek, Yilmazer Selma, Cağatay Penbe, Hatemi Hüsrev
Abstract excerpt
We studied the effect of variation at the lipoprotein lipase (LPL) gene locus on the susceptibility of individuals with non-insulin dependent diabetes mellitus (NIDDM) in a population of 110 NIDDM patients and 91 controls. Our objective was to study the relationship between the LPL-Pvu II polymorphism and NIDDM and lipid metabolism. PCR-RFLP was used to determine the DNA polymorphism of the sixth intron of the...
Topics
- Case-Control Studies
- DNA-Cytosine Methylases
- Diabetes Mellitus, Type 2
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Introns
- Lipoprotein Lipase
- Male
- Middle Aged
