Article
Beneficial effects of 'lamivudine pulse' therapy in HBeAg-positive patients with normal ALT*.
Journal of viral hepatitis - 1 Nov 2004
Sarin S K, Sandhu B S, Sharma B C, Jain M, Singh J, Malhotra V
Abstract excerpt
Currently no therapy is given to patients with chronic hepatitis B virus (HBV) infection who are HBeAg positive with normal alanine aminotransferase (ALT) levels. Steroid priming has been shown to enhance T-helper-1 (Th-1) cell response. Lamivudine may restore immunologic competence against HBV by causing a sudden decline in the level of the virus. We examined the efficacy of lamivudine pulse therapy on the...
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