Article
Alpha-1-antitrypsin levels and genetic variation of the alpha-1-antitrypsin gene in Peyronie's disease.
European urology - 1 Nov 2004
Hauck Ekkehard W, Hauptmann Arne, Haag Simone M, Bohnert Anette, Weidner Wolfgang, Bein Gregor, Hackstein Holger
Abstract excerpt
OBJECTIVES: Alpha-1-antitrypsin (alpha1-antitrypsin) is a major protease inhibitor controlling tissue degradation. Reduced alpha1-antitrypsin levels could result in a change of collagen metabolism. Previous studies have described decreased alpha1-antitrypsin levels in patients with Peyronie's disease. However, only a small number of patients were analyzed, and the reason for the decreased alpha1-antitrypsin...
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