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Article

Expression of SIBLINGs and Their Partner MMPs in Salivary Glands

1 Sept 2004

Abstract excerpt

Three members of the SIBLING family of integrin-binding phosphoglycoproteins (bone sialoprotein, BSP; osteopontin, OPN; and dentin matrix protein-1, DMP1) were recently shown to bind with high affinity (nM) and to activate 3 different matrix metalloproteinases (MMP-2, MMP-3, and MMP-9, respectively) in vitro. The current study was designed to document the possible biological relevance of the SIBLING-MMP...

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PMID: 15329369
DOI: 10.1177/154405910408300902

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