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Article

Base-By-Base: single nucleotide-level analysis of whole viral genome alignments.

BMC bioinformatics - 14 Jul 2004

Brodie Ryan, Smith Alex J, Roper Rachel L, Tcherepanov Vasily, Upton Chris

Abstract excerpt

BACKGROUND: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than gene content because two strains of an organism may share the same set of predicted genes but still differ in their pathogenicity profiles. For example, detailed comparison of multiple isolates of the smallpox virus genome (each...

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PMID: 15253776
DOI: 10.1186/1471-2105-5-96
PMCID: PMC481056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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