Article
Phenotypic and functional characterization of intraepithelial lymphocytes in a bovine ligated intestinal loop model of enterohaemorrhagic Escherichia coli infection.
Journal of medical microbiology - 1 Jun 2004
Menge Christian, Stamm Ivonne, van Diemen Pauline M, Sopp Paul, Baljer Georg, Wallis Timothy S, Stevens Mark P
Abstract excerpt
Ruminants are a major reservoir of enterohaemorrhagic Escherichia coli (EHEC), which cause acute gastroenteritis in humans with potentially life-threatening sequelae. The mechanisms underlying EHEC persistence in ruminant hosts are poorly understood. EHEC produce several cytotoxins that inhibit the proliferation of bovine lymphocytes in vitro and influence EHEC persistence in calves, suggesting that bacterial...
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