Article
Angiotensin-converting enzyme gene polymorphism in Behçet's disease.
Clinical rheumatology - 1 Apr 2004
Oztürk M Akif, Calgüneri Meral, Kiraz Sedat, Ertenli Ihsan, Onat A Mesut, Ureten Kemal, Ozbalkan Zeynep, Haznedaroğlu Ibrahim C
Abstract excerpt
Endothelial cell activation and/or injury is a characteristic feature of Behçet's disease (BD). The local renin-angiotensin system (RAS) in the vessel wall plays a prominent role in the endothelial control of vascular tonus and contributes to inflammatory processes. Angiotensin-converting enzyme (ACE) is the regulatory component of the RAS. In this study, we investigated the distribution of different alleles of...
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