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Article

Genome size: does bigger mean worse?

Current biology : CB - 23 Mar 2004

Charlesworth Brian, Barton Nick

Abstract excerpt

Genome sizes vary enormously. This variation in DNA content correlates with effective population size, suggesting that deleterious additions to the genome can accumulate in small populations. On this view, the increased complexity of biological functions associated with large genomes partly refle...

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Identifiers

PMID: 15043833
DOI: 10.1016/j.cub.2004.02.054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15043833-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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