Article
Respiratory complex I in brain development and genetic disease.
Neurochemical research - 1 Mar 2004
Papa Sergio, Petruzzella Vittoria, Scacco Salvatore, Vergari Rosaria, Panelli Damiano, Tamborra Rosanna, Corsi Patrizia, Picciariello Margherita, Lambo Rossana, Bertini Enrico, Santorelli Filippo Maria
Abstract excerpt
A study is presented on the expression and activity of complex I, as well as of other complexes of the respiratory chain, in the course of brain development and inherited encephalopathies. Investigations on mouse hippocampal cells show that differentiation of these cells both in vivo and in cell cultures is associated with the expression of a functional complex I, whose activity markedly increases with respect to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.