Article
Alanine glyoxylate aminotransferase deficiency: biochemical and molecular genetic lessons from the study of a human disease.
Advances in enzyme regulation - 1 Jan 1992
Watts R W
Abstract excerpt
The decision to treat a patient with primary hyperoxaluria type 1 (PHI) by combined liver and kidney transplantation, the former to correct the metabolic lesion which was then thought to be deficiency of cytoplasmic 2-oxoglutarate:glyoxylate carboligase, and the latter to replace the organ which...
Topics
- Alanine Transaminase
- Amino Acid Sequence
- Biological Transport, Active
- Humans
- Hyperoxaluria, Primary
- Liver
- Microbodies
- Mitochondria
- Molecular Sequence Data
- Mutation
- Protein Processing, Post-Translational
- Protein Sorting Signals
- Subcellular Fractions
- Transaminases