Article
[DNA repair in cells of the radiosensitive mutant of Drosophila rad(2)201GI after gamma-irradiation].
Genetika - 1 Sept 1992
Levina V V, Bil'din V N, Igusheva O A, Khromykh Iu M
Abstract excerpt
A radiosensitive mutant of Drosophila melanogaster rad(2)201GI was analysed for the capacity to repair DNA single- and double-strand breaks induced by gamma-rays. Analysis was performed on cell cultures derived from embryos of homozygous mutant stock and wild type strain Oregon R. The viability of irradiated cells was studied. It was shown that the mutant strain cells had increased lethality, just like a whole...
Topics
- Animals
- Cell Survival
- DNA Repair
- DNA, Single-Stranded
- Drosophila melanogaster
- Gamma Rays
- Genotype
- Mutation
- Radiation Tolerance