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Article

Founder mutations of CYP1B1 gene in patients with congenital glaucoma from the United States and Brazil

1 Jan 2004

Abstract excerpt

rimary congenital glaucoma is an important cause of childhood blindness worldwide. In congenital glaucoma, the anterior segment of the eye fails to develop completely; this results, in particular, in malformation of the trabecular meshwork and aqueous outflow pathways. 1 2 Although sporadic cases arise frequently, many cases of congenital glaucoma are inherited as an autosomal recessive trait, and the disease is...

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Identifiers

PMID: 14729846
DOI: 10.1136/jmg.2003.010777

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