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Article

Long distance PCR in detection of inversion mutations of F8C gene in hemophilia A patients.

General physiology and biophysics - 1 Jun 2003

Poláková H, Zmetáková I, Kádasi L'

Abstract excerpt

In the present paper, the experience with detection of intron 22 inversion of F8C gene in severe hemophilia A patients using a recently described long-distance PCR (LD-PCR) method was reported. To test the sensitivity and the specifity of the LD-PCR, analysis of 46 DNA samples of patients and their family members, previously tested by Southern hybridization, was performed. In addition, 16 DNA samples of severe...

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PMID: 14699993

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Source receipt: pubmed, retrieved 7 Sept 2026.

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