Article
GUG is an efficient initiation codon to translate the human mitochondrial ATP6 gene.
Biochemical and biophysical research communications - 16 Jan 2004
Dubot A, Godinot C, Dumur V, Sablonnière B, Stojkovic T, Cuisset J M, Vojtiskova A, Pecina P, Jesina P, Houstek J
Abstract excerpt
A maternally inherited and practically homoplasmic mitochondrial (mtDNA) mutation, 8527A>G, changing the initiation codon AUG into GUG, normally coding for a valine, was observed in the ATP6 gene encoding the ATPase subunit a. No alternate Met codon could replace the normal translational initiato...
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