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Article

Cloning and characterization of three PHEX homologues in Drosophila.

Journal of bone and mineral metabolism - 1 Jan 2004

Ito Mikiko, Akai Emiko, Izuka Michiyo, Segawa Hiroko, Kuwahata Masashi, Miyamoto Ken-ichi

Abstract excerpt

Inactivating mutations and/or deletions of PHEX ( Phosphate-regulating gene with Homologies to Endopeptidase on the X chromosome) are responsible for X-linked hypophosphatemic rickets in humans. In the present study, three Drosophila PHEX homologues (dPHEX-1, -2, -3) were isolated by the screening of a Drosophila cDNA library and expressed sequence tag (EST) database. The structural region involving motif II:...

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Source

Identifiers

PMID: 14691680
DOI: 10.1007/s00774-003-0440-8

Genes

PHEX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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