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Loop-Mediated Isothermal Amplification for Detection of African Trypanosomes

1 Dec 2003

Abstract excerpt

While PCR is a method of choice for the detection of African trypanosomes in both humans and animals, the expense of this method negates its use as a diagnostic method for the detection of endemic trypanosomiasis in African countries. The loop-mediated isothermal amplification (LAMP) reaction is a method that amplifies DNA with high specificity, efficiency, and rapidity under isothermal conditions with only...

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PMID: 14662933
DOI: 10.1128/jcm.41.12.5517-5524.2003

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