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Transduction of Porcine Enteropathogenic Escherichia coli with a Derivative of a Shiga Toxin 2-EncodingBacteriophage in a Porcine Ligated Ileal LoopSystem

1 Dec 2003

Abstract excerpt

In this study, we have investigated the ability of detoxified Shiga toxin (Stx)-converting bacteriophages Phi3538 (Deltastx(2)::cat) (H. Schmidt et al., Appl. Environ. Microbiol. 65:3855-3861, 1999) and H-19B::Tn10d-bla (D. W. Acheson et al., Infect. Immun. 66:4496-4498, 1998) to lysogenize enteropathogenic Escherichia coli (EPEC) strains in vivo. We were able to transduce the porcine EPEC strain 1390 (O45) with...

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PMID: 14660372
DOI: 10.1128/aem.69.12.7242-7247.2003

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