Article
Blood group does not correlate with disease severity in patients with Fabry disease (alpha-galactosidase A deficiency).
Blood cells, molecules & diseases - 1 Jan 2000
Linthorst Gabor E, Folman Claudia C, Aerts Johannes M F G, Hollak Carla E M
Abstract excerpt
Blood groups B and P1 are substrates for the lysosomal enzyme alpha-galactosidase A. Therefore, patients with alpha-Gal A deficiency and blood groups B or P1 may exhibit more severe disease. In 48 Fabry patients distribution of blood group was not different from that in the Dutch population. No p...
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