Article
[Human molecular genetics: from monogenic to polygenic or complex disorders].
Medecine sciences : M/S - 1 Oct 2003
Rousseau François, Laflamme Nathalie
Abstract excerpt
Human molecular genetics has successfully identified the genes involved in several monogenic disorders. It now aims at pinpointing the genetic determinants of polygenic or complex traits with a strong genetic component. This constitutes a new challenge. We discuss the methodological and practical aspects of identifying such genes as well as the challenges facing physicians that will have to use efficiently these...
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