Article
Do the genes that cause otosclerosis reduce susceptibility to otitis media?
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology - 1 Nov 2003
Manolidis Spiros, Alford Raye Lynn, Smith Richard J H, Ball Craig, Manolidis Leonidas
Abstract excerpt
HYPOTHESIS: The genetic factors that cause otosclerosis reduce susceptibility to otitis media. BACKGROUND: Susceptibility to some infectious diseases is modulated by host genetic factors. Genes that reduce the morbidity and mortality of infectious diseases may confer a selective advantage and achieve high-frequency in at-risk populations. Acute otitis media in the pre-antibiotic era frequently led to...
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