Article
Effect of asphalt fume inhalation exposure at simulated road paving conditions prior to bacterial infection on lung defense responses in rats.
Inhalation toxicology - 1 Nov 2003
Antonini James M, Roberts Jenny R, Taylor Michael D, Yin Xuejun, Stone Samuel, Moseley Amy, Ma Joseph K-H, Frazer David G, Castranova Vincent, Ma Jane Y C
Abstract excerpt
Asphalt fume inhalation has been suspected of affecting immune function in exposed workers. The objective of this study was to evaluate the effect of asphalt exposure on lung immune responses in rats using a bacterial infectivity model. Pathogen-free male Sprague-Dawley rats were exposed by inhalation to asphalt fumes (72.6 +/- 4.95 mg/m3) or filtered air for 6 h/day for 5 days. One day after the final asphalt...
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