Article
The dog genome: survey sequencing and comparative analysis.
Science (New York, N.Y.) - 26 Sept 2003
Kirkness Ewen F, Bafna Vineet, Halpern Aaron L, Levy Samuel, Remington Karin, Rusch Douglas B, Delcher Arthur L, Pop Mihai, Wang Wei, Fraser Claire M, Venter J Craig
Abstract excerpt
A survey of the dog genome sequence (6.22 million sequence reads; 1.5x coverage) demonstrates the power of sample sequencing for comparative analysis of mammalian genomes and the generation of species-specific resources. More than 650 million base pairs (>25%) of dog sequence align uniquely to the human genome, including fragments of putative orthologs for 18,473 of 24,567 annotated human genes. Mutation rates,...
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