[Phenotypic familial correlations of prostacyclin and thromboxane A2 levels in children and adolescents with or without hereditary predisposition to ischemic heart disease].

Abstract excerpt

The familial correlations of prostacyclin and thromboxane levels were examined in 90 children and adolescents from 70 families with hereditary coronary heart disease and in 56 of the same age from 38 families without hereditary atherosclerosis and their parents. The genetic factors were demonstrated to make a significant contribution to the phenotypic dispersion of prostanoids. The familial predisposition to the...

Topics

• Adolescent
• Child
• Coronary Disease
• Epoprostenol
• Female
• Humans
• Male
• Phenotype
• Thromboxane A2