Identification of a point mutation in factor XIII A subunit deficiency.

Article

Identification of a point mutation in factor XIII A subunit deficiency.

Blood - 15 Aug 1992

Board P, Coggan M, Miloszewski K

Abstract excerpt

Oligonucleotide primers have been designed for the amplification of all 15 exons of the human coagulation factor XIII A subunit gene. Each exon and its intron flanking regions has been amplified and sequenced from a patient with severe A subunit deficiency. A single G to A transition in the last...

Topics

Adolescent
Base Sequence
Exons
Factor XIII
Factor XIII Deficiency
Haplotypes
Humans
Introns
Male
Molecular Sequence Data
Mutation
Oligonucleotides
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
RNA Splicing

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