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Article

GM1 gangliosidosis in adults: clinical and molecular analysis of 16 Japanese patients.

Annals of neurology - 1 Mar 1992

Yoshida K, Oshima A, Sakuraba H, Nakano T, Yanagisawa N, Inui K, Okada S, Uyama E, Namba R, Kondo K

Abstract excerpt

Clinical findings were compared with the results of molecular analysis in 16 Japanese patients from 10 unrelated families with the adult/chronic form of GM1 gangliosidosis. Age of onset ranged from 3 to 30 years. Major clinical manifestations were gait and speech disturbances caused by persistent...

Topics

Adult
Age Factors
Alleles
Base Sequence
DNA Mutational Analysis
Enzyme Induction
Female
Gangliosidosis, GM1
Genotype
Humans
Male
Middle Aged
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Phenotype

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

beta-Galactosidase

Source

Identifiers

PMID: 1353343
DOI: 10.1002/ana.410310316

Genes

CGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1353343-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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