Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features.

doi:10.1093/brain/115.3.687

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Article

Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features.

Brain : a journal of neurology - 1 Jun 1992

Collinge J, Brown J, Hardy J, Mullan M, Rossor M N, Baker H, Crow T J, Lofthouse R, Poulter M, Ridley R

Abstract excerpt

A large family with autosomal dominant segregation of presenile dementia, and other neurological and behavioural features is described. At various times, family members have carried diagnoses of Alzheimer's disease, Huntington's disease, Parkinson's disease, myoclonic epilepsy, atypical dementia,...

Topics

Adult
Central Nervous System Diseases
Creutzfeldt-Jakob Syndrome
Female
Humans
Male
Middle Aged
Pedigree
Phenotype
PrPSc Proteins
Prions

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